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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d4b8ce77c2b7f086938f7be18da1c8c2223d0f4fdd48f0d24646053c29fde7' 
  AND token = 'YvBL5b8kq/TTB5mBYB63KdGtPDFnKBc7J+0CFKaN99k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}