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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bef8a320c71d5ff4f3cf0081e89a0d60f0f4374c2c66af17af92b9f16ec38c09' 
  AND token = 'QE0Wn/8+RFeGZ21N/YthzJDENnRbPEZzPIOalCpbsRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}