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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5349164e0aa5187008703255b3128db25f3a86f3e806254b765359c3f104723' 
  AND token = 'h0MLzgWQGbNB0bIeUWm4E1Rji1imrb+qTIRNkKCuKV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}