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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cade597a3e6db2335309587426ee516472e7c639aa233199ae569c0af751910a' 
  AND token = 'hOEKxHTVozOaPujP7nfh25g0OW/0zgSNS0SxuH0BVjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}