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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57eaf990f4b2712a1eff52e9e91956b47c09ec7ec999f13b0f9c68d86723a52f' 
  AND token = 'nVqG7IJDxop3u174P3gbQmRSIHhmnhaU74q9qSsWnnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}