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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23cb10922078fc7675e7052f21e8583ca448f6e98e17bd4217b5d46870fe135b' 
  AND token = 'GQ15AC4daIdYR+11fAoON9uz5zKud8gK+wGYpaaKjlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}