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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff7dfb1d8b4e52d9e54c31d6eac3b3883bdab466ba4800c26986208765861111' 
  AND token = 'bJWpE1Z/C+ZwcJa9/fDKm/MRteVU4AOwmtJTzaxWK9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}