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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e4fc2f91e9e02dd0ba9f3e23aab7ae4707d6338c0be49d89368dfc6019f0bf' 
  AND token = 'v2/fwZFcn/yNZ4w2ke4N67vcWNgX3Pg+ir/1p89Te38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}