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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab5ce741c6def778d6fe03bdd9384bdb1b9aaa67f0d39df636807f44a5d1956' 
  AND token = 'XxeqmEPw61avwPWpVecFYKk8EfIghumhZ5v4mEoLIqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}