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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d019eac8225c1b0772cb1c5987c9756c5d81d56a43c72cd0d91c3a3a88affe' 
  AND token = '/pqhN02WY0UnaGM06CN/hHcChA3MjloxkvD+Pgpe/Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}