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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5381f3f10671b68b8da7c0435de148b5d4130b8782c575e676f0f7e4b4891ebe' 
  AND token = '4i1amXbydscS2mj0Rqg1zdR+pzd5WsB/fM2uQTdncBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}