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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1716e8346d6a8797e472092d835b404bcb64bfb4351875e5cad7f25a552c3aa3' 
  AND token = 'SAs72XZs6U9Er0RhWzW3CryrlmRmQwd051jjUx4ozzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}