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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46d886c765cc035ce6fffea9a1ad248a2624b31f0b42567b2791ad8dbb262b2' 
  AND token = 'uVtwTMvf5tymtXdnZ7TFRGOW0Oi5To92Eq4uqflIZBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}