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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d40dea5f898481e885e007ee3f3ab854c8d512c305a1ff15521d370a1d1ffb2' 
  AND token = 'tNDeB3Aj59m1Oc+fSEECVvtVngungvEDL9OBvY1TAH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}