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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c649742f02812815cdcba9ae5a5f2afaf7c0c925addf793475ff7ffef2f2677' 
  AND token = '4fE5yReubdcUcefAtdXbwv5Peb5tK7gU9SPwSuZvog8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}