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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c274b9fdc40563c554d4cc6f56bf08e74cab47e504bad9d52e6aec17641c8b7' 
  AND token = 'GN65Vzw1lJmSycpzHRAW8ShUgFb+EszjF1wo42A1LhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}