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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac8854c364e1e09ef2ba21543a1d2be5187d6d05078cf58978ba0789d36663b' 
  AND token = 'NpHccnWZUlh8ovOEh8PbDwcnvEDJnJ6zXS08TTkbu4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}