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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ced64f27b84d3c8c0502ee392be33fb412c1c47d993ada05a538eb41da6fe9' 
  AND token = 'aNGUkNudYLVlOvlofu67NIFqUxtsY87b3OcxdFIx2Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}