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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385c5fbd011d5ec63fc13666a8fe9f5bd142a5a6b3f723fdeb6a5c17b489ad45' 
  AND token = '2gkj9tdapkxQFxixAmSFRf0VxM42xsM6c5ItWZ1SAvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}