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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59876b087200d840e4a0e0022f136be8112086ee13b3de9052b38774b1a183d7' 
  AND token = 'reU3fPdS6xOu7VvfViTE0O0QR83zCHPDfVjgZ6+wRRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}