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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254b4ee74de18b69d37e9edf10275aaa868fcbd1394b7bd99ceb8b10084545b7' 
  AND token = 'ZtAW8NPFan6AQOdzkv+02JR+j2Nh22eubuXtY6LifKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}