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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b857c4eba4c55f3e9a8f7c603c2e53e0a2bffe77f45c5382eab2aeff40cb537' 
  AND token = 'sJih0PX+vyL417fDqbQZTH46oAguatfjkL4ucDfK/mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}