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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405b9fcb664a7950892b9b35268353f217ba60cb5c9b3e07fe4f604934cf2a6a' 
  AND token = 'aWYgq7YAfTbnOU0n9vb7PxpIWfKGCL5kM++8I0lO2Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}