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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2bff235d2603887d5ace65b7d61d3193a5b3d2897db0936e43bc9794584195' 
  AND token = 'CKHIIqdyFF6JANlA//272ajZN75GF7EUHBtw5Gg6ybA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}