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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecbc8f8267a3994e578531674a07692e4da3a1ab24ad067c58f3b733d3daaee' 
  AND token = 'uZaO3QF1Vdn0lYup3pMOIXIBe1/7P4SZYCuzfBy1k0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}