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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad99d944401650fc607b5ec2d42d7c9e07f418eb98ae051fca240e81a4b5182' 
  AND token = '408iJPOt4H71/LcZV1rjNDwTYzaXY4jmi4qHkmLXGPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}