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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c976c13a95cf3dc52dbd88c0b7bb7310b7b2ff7516e80c6c5fafb290efd35299' 
  AND token = '0eTwQMDWr7deFiPVAeiJ1zxDeMkOLrqYDuJF3aL+2Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}