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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483c6807e2c170ea1ec07cfe99b8fddb4527554098d561c6edc20a813e70801a' 
  AND token = 'EMCWEHBjyG+dt6wEi/X3YC4E9E/w5iYdGCrHiPUlEMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}