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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd597e942182dfd35ec88b45cf351ace6959e137b510cc9232c26650ee44b3836' 
  AND token = 'v0qjkWtEvs+E3+SwiNTuv5sErOk1JzZDyS0HDNeRrcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}