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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22eae1ae50d67263d6b7449ec3177583aa3ca3600d55684c543e0938731e8f67' 
  AND token = 'OwBmQUzlscLzgr5HHHFTqSH2iyJGgB87IXXw9Kl8sxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}