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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f48f25c01e4fd71e0759fc175bad14af6b59cb789300b188704c769f7cd78d9' 
  AND token = 'ZVqiSAI2B1pMAln6to1uVONXbaxS+m3ZahA4LENUsuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}