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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '564c35e16390e5402cc207d1f5dc878f0bb8c8b349cfca5d047517d76254978e' 
  AND token = '3PR25quaf0bc53lL//c3u92PUqv4g//iArqvN2kr2aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}