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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514016824fbe04907e665c49e709237c55a10b257b9003de5935e538447bc1fd' 
  AND token = 'ZH/7vYB5M+pYv+4+11iJtH1+QX+AMCaqVgrNz6d3REQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}