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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8156ba87fb2c4baaab5dddd82c50143c3fadf5761779b7ebe4414217f8e28f54' 
  AND token = '+nzjx33pHk356F/Wbs5YlVAiEwbi6cmicNy4zRdBntk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}