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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6e8c8b49e51e0637720d1d00f7e4f047aa91f0c26cee40b4495d3570e7693d' 
  AND token = 'SpSK3GdvqNLC/DCdgiMBCCzRqY0PjaN1NUKs9HtYvoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}