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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e764376d6fb7ed7aae95bcadd1f5c2e5ae2712c82148236b65cd0c75084360b' 
  AND token = 'EhUD3h8xi/4MUS6PQeM3s3p/3o9MBKE+7sW/Fo49owA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}