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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afddff3fafdda641c73a7728bb4e79d6177f5339c675c897dd7280d0409e43a' 
  AND token = 'jnKsCRe7NgFkwjs+Cjm8eiWzP7C2k/uX72gO93EJjMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}