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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac0e7b22ff5780575720e88302be4a2ddbe99c3eb2a5a749e3e25b22caf8d43' 
  AND token = 'VJzzZUdFjvY8ktRhuMBi33hQkNPP9iT31Tp36hnamO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}