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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2dabf2e0a231968458b2ac39efa18a6ae179164d2608e05db5d52d7940403b' 
  AND token = 'NXrsRD40z1Zq5DNGELwbWLY5IYYnOQajZNA98KnCtzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}