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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2935e8915ba9418476443d1c221fffa8ca132b7bd5cc22b18ad0113ef26b08' 
  AND token = 'CYnDSuBB49YH6gdwPwGQuP7MpDMAHv4Dob9CS+WQiu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}