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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072b12876a4c68f204c4b98d93a9fcc885ba03d9c798a36e55d8d95d7dadae24' 
  AND token = 'HAtAFKd1DpjGDssAcUjzt/JwlWvSYkoF7lz+R5jyHNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}