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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc22037d5109fb6b0871a4d78b8ac194cc9b9e21fa838488720d79ef222510f9' 
  AND token = 'f8pWQ97JIvy4BLvMbNW+2sBn4b5TzwOO8Ytm6JmF0EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}