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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25616d95024de3bb294b63418f76232cdd249776cbc7ba0ceb58b43df96ad083' 
  AND token = 'EigKTF56GQdxCVFF3OnAdiysq7j3aCNNu58Dtqcg8XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}