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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd0fb999e688ed5388ff1acd3663f0d41e0f1a6d62648e00d849a29f3953408' 
  AND token = 'ulDGi2ERxvnQEI3MeblEoNq5Cin9XdswyTVdYYfaO3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}