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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '138930691a9c7fcd2f24134bf2fc4a4de581d35d6754e52f40303617c47429c4' 
  AND token = 'lQD34yTo1pgOBOio9YImtcVv0GMnfQmgogKTaxWadH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}