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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb22e2a6000d3ca658f94522d4b09106a596a048a638e5d17319ea445e71fba8' 
  AND token = '6cXuCabKuHla96Iq78sijMxnS3AdRG+Xiqp7TxLVuEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}