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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f628371a6fe14f16d19f1fbd6f8620ec0937da9681fbd83df9fa260a3e93d734' 
  AND token = 'RitVLmhD8so7TzQTPd/rSUsRzHr+R+/Y0tKPWCYbMrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}