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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98ad0a4df9d1ef40745e7347e2ab717908c49c8c5295454748f4a9ca66b25de0' 
  AND token = 'xv8QV99chtwyRLCUG6+M4rGYw2GtUGBJ8jbvAsXiSm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}