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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628b4cbc0751e4fd3fc5eb893282bb403ed342c7dda9a9541fa602a29cb3197c' 
  AND token = '5xEM2TtSmeFt/hs2cm4h00TB/SLNm/S9wspob867g24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}