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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4703d9a9088591de2fbe047c6a6139e9e58b243a0c61e649634a8e169c828a' 
  AND token = 'itJ4Yho4mQCmDq6e+TrnC2hOGF3Z0wP9u869kshTx7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}